SkinPen Indication

Reveal your skin’s natural clarity and confidence with SkinPen Precision, a clinically proven treatment designed to rejuvenate and repair. From acne scars and stretch marks to fine lines, wrinkles, enlarged pores, and uneven skin tone, SkinPen helps restore smoother, healthier, and more radiant skin.

Introduction to Acne Scars

Mechanism of Action:

  • Mechanically breaks down scar tissue.
  • Activates cellular enzymes known as matrix metalloproteinases, or MMPs.
  • Remodels scar tissue through the proper deposition of collagen and elastin.
  • Addresses the red and purple discoloration associated with acne scars by increasing blood flow.
  • Addresses the brown discolorations, or post inflammatory hyperpigmentation (PIH), associated with acne scars by stimulating the skin’s natural growth factors.

Female | Procedures: 6 Photos courtesy of: Cathy A. Presnick, Licensed Aesthetician; A Perfect Complexion, LLC, Melbourne, FL

BEFORE

AFTER

Introduction to Dyschromia

Mottled Hyperpigmented Lesions/Patches

Mechanism of Action:

  • Induce keratinocyte turnover and “restore” the normal pigment activity of melanocytes in over pigmented areas.
  • This occurs at the dermal-epidermal junction (DEJ).
  • This DEJ-shallow dermis area is the target depth to microneedle. See arrows where microchannels are formed

Epidermal melanin density in melasma before procedure

Reduction in epidermal melanin density 1 week after microneedling procedure

Before

After

Pigmentation Conditions

Mechanism of Action:

  • Induce keratinocyte turnover and “restore” the normal pigment activity of melanocytes in over pigmented areas.
  • This occurs at the dermal-epidermal junction (DEJ).
  • This DEJ-shallow dermis area is the target depth to microneedle. See arrows where microchannels are formed

Hypopigmented Patches

Mechanism of Action:

  • Induce the activation, migration, and/or proliferation of melanocytes into hypopigmented areas at the dermal-epidermal(DEJ). This shallow dermis area is the target depth.
  • Also, mechanical trauma stimulates the melanocytes migration from the pigmented areas to unpigmented areas.
  • Microneedling may increase the number of pigment cells and stimulate more pigment production
  • Studies in literature indicate that 6 or more treatments may be necessary to begin to see improvement

Stimulates melanocyte migration to restore pigment and smooth rolling scars.

Microchannels provide space for melanocytes to migrate into non-pigment areas

Introduction to Surgical Scars

Each year in the developed world 100 million patients acquire scars, some of which cause considerable problems, as a result of 55 million elective operations and 25 million operations after trauma. There are an estimated 11 million keloid scars and four million burn scars, 70% of which occur in children.

Mechanism of Action:

  • Mechanically breaks down scar tissue.
  • Activates cellular enzymes known as matrix metalloproteinases, or MMPs.
  • Remodels scar tissue through the proper deposition of collagen and elastin.

Global Assessment Score = 4. Alster, Tina S. M.D.; Li, Monica Ka Yi M.D. Microneedling of Scars: A Large Prospective Study with Long-Term Follow-Up, Plastic and Reconstructive Surgery: February 2020 – Volume 145 – Issue 2 – p 358-364 doi: 10.1097/PRS.0000000000006462

Surgical scar on the nose before

6 months after two microneedling treatments.

Introduction to Stretch Marks

Stretch marks can be caused by an overextension of the skin. Can be found on men and women but 2x more frequent on women. There is little evidence for avoidance other than well moisturized skin. Stretch marks tend to start as red discoloration and age to atrophic white stretch marks

Mechanism of Action:

  • Promotes removal of old damaged collagen
  • Induces keratinocytes proliferation that releases growth factors to promote collagen deposition by the fibroblasts and elastin deposition
  • Modulates the expression of several genes in the skin (vascular endothelial growth factor, fibroblast growth factor, epidermal growth factor, collagen type I and III) that promote extracellular matrix remodeling

Kui Young Park et al. Dermatol Surg 2012;38:1823–1828

Before

After

Introduction to Fine Lines and Wrinkles

Considered a part of the aging process of the skin. This aging process is accompanied with structural and functional changes in extracellular matrix components such as collagen and elastin which can result in the appearance of fine lines and wrinkles.

Zhang, S., & Duan, E. (2018). Fighting against Skin Aging: The Way from Bench to Bedside. Cell transplantation, 27(5), 729–738. https://doi.org/10.1177/0963689717725755 7

Mechanism of Action:

  • Promotes removal of old damaged collagen
  • Induces keratinocytes proliferation that releases growth factors to promote collagen deposition by the fibroblasts and elastin deposition
  • Modulates the expression of several genes in the skin (vascular endothelial growth factor, fibroblast growth factor, epidermal growth factor, collagen type I and III) that promote extracellular matrix remodeling

Female, Age: 66, Procedures: 2. Photos courtesy of Christina Clarke, Registered Nurse Bio-Health & Aesthetics, Mount Pleasant, SC

Before

After

Introduction to Enlarged Pores

Enlarged skin pores are visible surface irregularities caused by high sebum production, reduced elasticity, increased follicle size, and factors like acne, hormones, and skincare habits.

Crown Clinic, Mona Alqam, MD.

Mechanism of Action:

  • Promotes removal of old damaged collagen
  • Induces keratinocytes proliferation that releases growth factors to promote collagen deposition by the fibroblasts and elastin deposition
  • Modulates the expression of several genes in the skin (vascular endothelial growth factor, fibroblast growth factor, epidermal growth factor, collagen type I and III) that promote extracellular matrix remodeling

Female, Procedures: 4. Crown Clinic, Mona Alqam, MD.

Before

After

Discover how beautifully simple it is to uncover the true you with SkinPen.

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